David S. Goldstein
Curriculum Vitae
February, 2006
Born in Newark, NJ, June 23, 1948.
Family
Married
11/1972 to Minka Krasow of Danbury, Conn. Children: Yakira, born 11/1974;
Samuel, born 6/1976; Zvi, born 4/1978; Mona, born 5/1982; Joseph, born 1/1990.
Address
and phone
7711 Fontaine Street
Potomac, Maryland 20854
(301) 299-2201
e-mail: daveg@his.com
Clinical Neurocardiology Section
NINDS, NIH
Building 10 6N252
10 Center Drive, MSC-1620
Bethesda, Maryland 20892-1620
(301) 496-2103
FAX: (301) 402-0180
e-mail: goldsteind@ninds.nih.gov
Education,
Employment, and Appointments
Weequahic High School, Newark, NJ, 1962-1965.
Phillips Academy, Andover, Mass, 1965-1966.
Yale College, New Haven, CN, 1966-1970. Graduated Cum Laude with Honors with Exceptional Distinction in Psychology.
Johns Hopkins School of Medicine, Baltimore, MD, 1970-1976. MD, PhD in Behavioral Sciences. Dissertation: Instrumental Cardiovascular Conditioning.
Summer
exchange fellow in cardiovascular physiology, Department of Physiology, Oxford
University, Oxford, England, 1971.
Medical internship and residency, University of Washington Affiliated Hospitals, Seattle, WA, 1976-1978.
Clinical Associate, National Heart, Lung, and Blood Institute, Bethesda, MD, 1978-1982.
Medical Staff Fellow, National Heart, Lung, and Blood Institute, Bethesda, MD, 1982-1983.
Senior Investigator, National Heart, Lung, and Blood Institute, Bethesda, MD, 1983-1990.
Consultant Physician, The Washington Clinic, Washington DC, 1985-1994.
Promotion (to GM-14 from GM-13), 5/1989.
Promotion (to
GM-15 from GM-14), 3/1992.
Chief,
Clinical Neurochemistry Section, Clinical Neuroscience Branch, National
Institute of Neurological Disorders and Stroke, Bethesda, MD, 1992-1999.
Converted to
Title 38 position, 1997.
Converted to
Title 42 position, 2003.
Senior Fellow,
Institute for Defense Analysis/National Institutes of Health, Bethesda, MD,
2003-2004.
Current
Attending Physician, Clinical Staff, The Clinical Center, NIH, Bethesda, MD, 1983-date.
Senior Investigator, National Institute of Neurological Disorders and Stroke, Bethesda, MD, 1990-date.
Clinical Associate Professor of Medicine (Cardiology), Georgetown University School of Medicine, Washington, DC, 1989-date.
Visiting Professor of Medicine, the Johns Hopkins University School of Medicine, Baltimore, MD, 1999-date.
Visiting Professor of Medicine, Sackler Faculty of Medicine, Tel Aviv University, Israel, 2004-date.
Chief,
Clinical Neurocardiology Section, Clinical Neurosciences Program, Divison of
Intramural Research, National Institute of Neurological Disorders and Stroke,
Bethesda, MD, 1999-date.
Certifications
and Authorizations
Board certified in internal medicine, ABIM No. 69707, 9/12/1979-date.
Authorized User for Human Use of Radioactive Materials, NIH Radiation Safety Committee
3H-Norepinephrine
3H-Epinephrine
131I-Albumin
Certified in Advanced Cardiac Life Support, American Heart Association, 1983-date.
Investigational New Drug Applications (Active)
#21,220 Yohimbine hydrochloride
#33,866 6-[18F]Fluorodopamine (Sponsor= P. Herscovitch)
#35,513 6-[18F]Fluorodopa (Sponsor= P. Herscovitch)
#40,747 [13N]-Ammonia (Sponsor= P. Herscovitch)
#63,002 Trimethaphan
#67,315 Tyramine hydrochloride
#67,729 Acetylcholine
#71,374 Pentolinium
Licensed to practice medicine in the State of Maryland, #D23433, 1979-date.
Honors
Cum Laude Society and National Honor Society, 1965-1966.
Dean's List, Yale College, 1966-1970. Eugene Meyer Memorial Scholarship, Yale College, 1966-1970. Graduated Cum Laude with Honors with Exceptional Distinction in Psychology, Yale College, 1970. Recipient, Angier Prize for Research in Psychology, Yale College, 1970.
Elected, American Society of Clinical Investigation, 5/1990.
Visiting
Professor in Medicine, Faculty of Health Sciences, Ben-Gurion University of the
Negev, 1986.
Elected to Membership, American Society of Clinical Investigation, 5/1990.
Visiting
Professor, Chaim Sheba Medical Center, Tel Ha-Shomer, Israel, 6-8/1993.
Pfizer
Lecturer, Clinical Research Institute of Montreal, 5/1994.
Recipient, Merit Performance Cash Award, NIH, 1989, 1990, 1991, 1992, 1993, 1994, 1996. Merit Pay bonus recipient, NIH, 1985-1994, 1996.
Recipient, Willem Laufberger Medal, Czech Academy of Sciences, Prague, Czech Republic, 7/1994.
Recipient, NIH Merit Award, 1994.
Elected to
Fellowship, Council for High Blood Pressure Research, American Heart
Association, 1996.
Elected to
Fellowship, Council on Circulation, American Heart Association, 1996.
Recipient, NIH
Staff Recognition Award, 3/2000.
Recipient,
Group NINDS Merit Award, “for excellence in patient-oriented clinical
research,” 6/2000.
Elected to
Fellowship, American Heart Association, 4/2001.
Recipient,
Presidential Executive Director’s Award, National Dysautonomia Research
Foundation, 7/2002.
Saul Farber
Distinguished Lecturer, Tel Aviv University Sackler School of Medicine, Israel,
10/2002.
Recipient, NIH Distinguished Clinical Teacher Award, 9/2004.
John L. Decker Memorial Lecturer, NIH Clinical Center, 6/2005.
Special Recognition Award for exceptional mentoring, NINDS, 12/2005.
Active Clinical Research Protocols (PI=Principal
Investigator)
03-N-0004 Clinical Laboratory Evaluation of Primary Chronic Autonomic Failure. PI=D.S. Goldstein (Radiation Safety Authorization No. 1928)
03-N-0007 Characterization & Identification of Paroxysmal Hypertensive/Hypercatecholamine Syndromes. PI=G. Eisenhofer (Radiation Safety Authorization No. 1925)
03-N-0314 Clinical Laboratory Evaluation of Chronic Orthostatic Intolerance. PI=D.S. Goldstein (Radiation Safety Authorization No. 1943)
05-N-0024 Non-Pharmacologic Therapy of Neurocardiogenic Syncope. PI=B. Eldadah.
06-N-0047 Reference Values for Plasma Catechols. PI=D.S. Goldstein.
Post-doctoral researchers and their subsequent positions
Arno Zaritsky, MD (Children's Hospital, Wash., DC, 1986) Director, Intensive Care Unit, Children's National Medical Center, Washington, DC
Reuven Zimlichman, MD (Israel, 1984-1987) Chief of Medicine, Wolfson Hospital, Cholon, Israel
David
Hovevey-Sion, PhD (Israel, 1986-1988)
Peter Chang, MD (Holland, 1988-1989) Department of Nephrology, Univ. of Leiden, The Netherlands
Moshe Garty,
MD (Israel, 1987-1988) Chief of Medicine, Rabin Medical Center, and Director,
Recanati Center for Medicine and Research, Petach Tikve, Israel
Ehud Grossman,
MD (Israel, 1988-1990) Professor of Medicine, Tel Aviv University, and Chief of
Medicine, Chaim Sheba Medical Center, Tel-Hashomer, Israel
C.Y. Chai, PhD
(Taiwan, 1989)
Katalin
Szemeredi, PhD (Hungary, 1986-1990) President, Egis Pharmaceuticals, Budapest,
Hungary
Marye Tamrat,
MD, PhD (Howard University School of Medicine, 1989-1990) Associate Professor
of Medicine (Intensive Care), Howard Univ., Washington, DC
Maria Ines
Armando, PhD (Argentina, 1989-1992) Faculty, Centro de Investigaciones
Endocrinologicas, Hospital de Ninos "R. Gutierrez," Buenos Aires,
Argentina
Efrat
Wolfovitz, MD (Israel, 1991-1992) Chief, Department of Medicine, Rothschild
Hospital, Haifa, Israel
John Finberg,
PhD (Israel, 1991-1992) Faculty, Rapaport Center, Univ. of Haifa, Israel
Jacques
Lenders, MD (Holland, 1991-1992) Faculty, Department of Medicine, St. Radboud
University Hospital Nijmegen, The Netherlands
Anna
Deka-Starosta, MD (Poland, 1986-1994)
Gal Yadid, PhD
(Israel, 1991-1994) Faculty, Dept. of Life Science, Bar-Ilan Univ., Ramat-Gan,
Israel
John
Stuhlmuller, MD (USA, 1993-1995) US FDA
Olga Tjurmina,
PhD (Russia, 1996-1998) Health Science Administrator Training Program, NIH
Cees Tack, MD,
PhD (The Netherlands, 1997-1998) Faculty, Department of Internal Medicine, St.
Radboud University Hospital Nijmegen, The Netherlands
Stephen G.
Kaler, MD (USA, 1995-1999) Clinical Director, National Institute of Child
Health and Human Development, NIH.
Jigisha Patel,
MD (United Kingdom, 1999-2000) Post-doctoral Fellow, University College,
London, UK
Simon Bruce,
MD (USA, 1998-2000) SmithKline Beecham, Inc.
Karel Pacak,
MD (Czech Republic, 1990-1995, 1997-2000) Senior Investigator, National
Institute of Child Health and Development, NIH
Patricia
Villemagne, MD (Argentina, 1999-2000) Department of Nuclear Medicine, Johns
Hopkins Hospital
Steven M.
Frank, MD (USA, 1999-2000) Department of Anesthesiology, Greater Baltimore
Medical Center, Baltimore, MD
Sheng-Ting Li
, MD, PhD (China, 1998-2003), Nuclear Medicine Technologist, Nuclear Medicine
Department, CC, NIH
Yehonatan
Sharabi, MD (Israel, 2001-2003), Head, Hypertension Research Unit, Department
of Medicine, Chaim Sheba Medical Center, Tel HaShomer, Israel
Dnyanesh
Tipre, PhD (India, 2004-2005) Visiting Fellow, NCI
Current
Graeme Eisenhofer, PhD (New Zealand, 1985-1988, 1991-1998), Staff Scientist, NINDS
Basil Eldadah,
MD (USA, 2002-date), Clinical Fellow, NIH
Yehonatan
Sharabi, MD Clinical Fellow (Title 42, Part-time)
Ahmed Saleem, MD
(Iraq, 2004-date) Clinician
Current Collaborations within and outside
NIH
Within
NIH
Collaborator Institution Topic
Csako CC Plasma
catechols and metanephrines assays (GE)
Dionne NIDCR Neurotropin™ for Complex Regional
Pain Syndrome (Clinical
Protocol 00-D-0200)
Eisenhofer NINDS (CNCS) Pseudopheochromocytoma
(Clinical
Protocol 03-N-0007)
Eldadah NINDS
(CNCS) Relationship of
autonomic function to hypnotic
susceptibility
(Clinical Protocol 03-N-0199)
Elkahloun NIHGR Microarray
studies of pheochromcotyoma (GE)
Innis NIMH NET
ligand development
Kaler NICHD Neurochemical
testing in Menkes disease (Clinical
Protocol
90-N-149)
Kirk NIDDK Catecholaldehydes
Merke NICHD/CC Congenital adrenal
hyperplasia (Clinical Protocol 01-
CH-0096)(GE)
Pacak NICHD Clinical evaluation of
pheochromocytoma (Clinical
Protocol
00-CH-93)(GE)
Outside NIH
Collaborator Institution Topic
Appenzeller NMHEMC
Res. Fdn. Autonomic function in
chronic hypoxia
Bauman/ VAMC Bronx NY Catecholamine systems and NO in tetraplegia
Wecht
Bornstein Univ. of Heidelberg Adrenocortical
regulation of adrenomedullary Germany
(GE) function
Charney Mt. Sinai Sch. Med. Alpha-2
adrenoceptor subtype polymorphisms
Freeman/ Deaconess, Boston L-DOPS
for neurogenic orthostatic hypotension
Kaufmann Mt. Sinai, NY L-DOPS
for neurogenic orthostatic hypotension
Geller/Sun Children's Hosp. Boston Gene
therapy in an animal model of Parkinson’s disease
Lambert Baker Med. Res. Inst. NGF
in autonomic failure
Australia
Lenders Univ. of Nijmegen Neurochemical
diagnosis of pheochromocytoma (GE)
The
Netherlands
Neumeister Yale Alpha-2
adrenoceptor subtype polymorphisms
Phillips Murdoch Univ. Pheochromocytoma cell
biology (GE)
Australia
Sharabi/ Tel-Aviv Univ. Primary and secondary abnormalities of
Grossman Israel catecholamine
systems in cardiovascular diseases
Memberships:
Societies (Current)
Member, American Society of Clinical Investigation, 1990-date.
Member, American Heart Association, 1992-date.
Member, International Society for the Investigation of Stress, 1992-date.
Member, American Autonomic Society, 1992-date.
Member, American Physiological Society, 1996-date.
Member, Neural
Control and Autonomic Regulation Section, American Physiological Society,
1997-date.
Fellow, American College of Physicians, 1986-date.
Fellow, Council for High Blood Pressure Research, American Heart Association, 1996-date.
Fellow, Council on Circulation, American Heart Association, 1996-date.
Founding Member, Association for Patient-Oriented Research, 1999-date.
Member, American Academy of Neurology, 2000-date.
Member,
Autonomic Nervous System Section, American Academy of Neurology, 2000-date.
Memberships: Committees and Boards (Current)
Editorial
Board, Homeostasis, 1993-date.
Editorial
Board, Stress, 1995-date.
Chairperson,
Advisory Board, The Foundation for Catecholamine Research, 1997-date.
Board of
Directors, National Foundation for Dysautonomia Research, 2000-date.
Editorial Board,
Clinical Autonomic Research, 2001-date.
Executive
Board, American Autonomic Society, 2002-date.
Founder,
Scientific Integrative Medicine Interest Group, NIH, 2004-date.
Member, Intramural Research Board (IRB), National Institute of Neurological Disorders and Stroke, NIH, 2004-date.
Executive Board, Autonomic Nervous System Section, American Academy of Neurology, 2004-date.
Executive Board, Association for Patient-Oriented Research, 2005-date.
Plenary/Named Lectures
Plenary
lecture, “New clinical techniques to assess sympathetic innervation and
function.” Ninth Conference of the American Autonomic Society, Sanibel Island,
FL, 10/1998.
Combined
Plenary Lecture, “Cardiac sympathetic denervation in Parkinson’s disease,”
Ninth International Catecholamine Symposium and Fifth International Symposium
on Parkinson’s and Alzheimer’s Disease, Kyoto, Japan, 4/2001.
Plenary
Lecture, “Applying functional neuroimaging to autonomic disorders,” Thirteenth
Annual Meeting, American Autonomic Society, Hilton Head, SC, 10/2002.
Plenary
Lecture, “Visualizing sympathetic innervation of the heart,” Third World
Congress on Heart Disease, Washington, DC, 7/2003.
John Laws
Decker Memorial Lecture, “Concepts of scientific integrative medicine,” NIH,
Bethesda, MD, 6/2005.
Invited
Presentations
Invited
participant, “Biochemical measures of reactivity,” Conference on Stress,
Reactivity and Cardiovascular Disease, University of Pittsburgh and NHLBI, 1984
Invited
speaker, “Catecholamines in plasma and cerebrospinal fluid: Sources and
meanings,” Brain Peptides and Catecholamines in Cardiovascular Regulation in
Normal and Disease States, University of Houston College of Pharmacy, Houston,
TX, 1/1986
Invited
lecture, “What an Internist Should Know about the Sympathetic Nervous System,” George
Washington University Medical Center, Washington, DC, 10/1986.
Invited
participant, NIH Conference on the Mechanisms of Physical and Emotional Stress,
Bethesda, MD 11/1986
Invited
lecture, “Plasma Catecholamine Kinetics in Stress & Hypertension,” University
of Maryland Hypertension Center, Baltimore, Md, 11/1986
Invited
lecture, “New Approaches in the Clinical Assessment of Sympathetic Activity
using Plasma Catecholamines, DOPA, and DHPG,” Catecholamine Club, FASEB, 3/1987
Invited
lectures, “Plasma levels of DOPA, DHPG, and catecholamines in the clinical
assessment of sympathetic activity,” the Hypertension Society, and “Estimation
of cardiac norepinephrine release and neuronal uptake in man,” the
Cardiovascular Division, Mayo Clinic, Rochester, MN, 5/1987
Invited
lectures, “Plasma levels of DOPA, DHPG, and catecholamines in the clinical
assessment of sympathetic activity,” and “Estimation of cardiac norepinephrine
release and neuronal uptake in man,” Division of Cardiology, Toronto General
Hospital, Toronto, Ontario, Canada, 5/1987
Invited
speaker, “Plasma catecholamine responses to stress in essential hypertension,”
Fourth Symposium on Catecholamines and Other Neurotransmitters in Stress,
Smolenice Castle, Czechoslovakia, 6/1987
Invited
lecture, “Source and Meaning of Endogenous DOPA,” Department of Neurology,
USUHS, Bethesda, MD, 9/1987
Invited
speaker, “Stress and Cardiovascular Disease,” Pennsylvania Claims Association,
Philadelphia, PA, 1/1988
Invited
lecture, “Physiology of Hypertension: Possible Mechanism for ECMO
Hypertension,” 4th Annual Children's Hospital National Medical Center ECMO
Symposium, Snowmass, CO, 2/1988
Cardiology
Grand Rounds, “New clinical approaches for assessing cardiac sympathetic
function,” Yale School of Medicine, New Haven, CN, 4/1988
Invited
lecture, “Plasma Catecholamines in Human Hypertension,” Symposium on
Sympathetic Function and Human Hypertension, International Society of
Hypertension, Sapporo, Japan, 5/1988.
Invited
speaker, “Implications of measurements of plasma catechols in hypertension,”
symposium on “Blood Pressure Mechanisms and the Sympathetic Nervous
System--from Molecules to Man,” American Society of Hypertension, New York
City, NY, 6/1988
Suburban
Hospital Seminar, “Stress, the Sympathoadrenomedullary System, and Disease,”
Suburban Hospital, Bethesda, MD, 9/1988
Invited
lecture, “Clinical applications of plasma levels of catechols in hypertension,”
American Association for Clinical Chemistry, 10/1988.
Invited
lecture, “Clinical assessment of sympathetic nervous system activity,” Sociedad
Argentina de Investigacion Clinica, Buenos Aires, Argentina, 11/1988
Invited
lectures, “Stress-Induced Activation of the Sympathetic Nervous System,” and
“New Techniques for Clinical Assessments of Sympathetic Activity,” Major
Conference Series, Department of Psychiatry, University of Michigan, Ann Arbor,
Michigan, 2/1989
Invited
lecture, “The sympathetic nervous system and hypertension,” Howard University
School of Medicine, Washington, DC, 2/1989
Invited
presentation, “Assessment of sympathetic activity using new drug probes and PET
scanning,” Gerontology Research Center, NIA, Baltimore, MD, 6/1989
Invited
seminar, “New ideas about stress and the sympathoadrenomedullary system,”
Department of Physiology & Biophysics, Georgetown University School of
Medicine and Dentistry, Washington, DC, 11/1989
Clinical
Center Grand Rounds, “Heartstrings: New techniques for clinical assessment of
the sympathetic nervous system,” Clinical Center, NIH, Bethesda, MD, 12/1989
Invited
lecture, “Norepinephrine kinetics in hypertrophic cardiomyopathy,” Cardiology
Branch, NHLBI, 1/1990
Invited
lecture, “Neurotransmitters and stress,” 21st Annual Meeting, Association for
Applied Psychophysiology and Biofeedback, Washington, DC, 3/1990
Invited lecture,
“Plasma dopa levels and sympathetic nervous activity,” 13th Meeting of the
International Society for Hypertension, Montreal, Quebec, Canada, 6/1990
Faculty,
“Catecholamines,” Gordon Conference, 7-8/1990
Invited
lecture, “Sympathetic activity and reactivity in essential hypertension:
Application of a yohimbine challenge test,” Irvine H. Page International
Hypertension Research Symposium, National Hypertension Association, Baltimore,
MD, 9/1990
Invited
participant, Hypertension Collegium 1990, Laguna Niguel, CA, 10/1990
Invited
lecture, “Clinical Applications of Monitoring Catechols,” Waters Neuroscience
Symposium, Rockville, MD, 12/1990
Invited
panelist, “The Transit 'Hot Seat'. A National Transit Labor/Management
Conference.” Miami, FL, 2/1991
Invited lecture,
“Positron emission tomographic scanning of cardiac sympathetic innervation and
function,” for the Symposium, “Advances in Integrative Neurocirculatory
Physiology,” FASEB, Atlanta, GA, 4/1991
Invited
lecture, “Clinical uses of catechols in the assessment of sympathoadrenal
activity in stress and disease,” Fifth Symposium on Catecholamines and Other
Neurotransmitters in Stress, Smolenice, Czechoslovakia, 6/1991
Invited
presentation, “Stress and hypertension: Is there a sympathoadrenal link?”
Annual meeting, The Pavlovian Society of North America, Baltimore, MD 9/1991
Co-chairperson,
Scientific Sessions, Second International Conference on the Shy-Drager
Syndrome, Vanderbilt University, Nashville, TN, 10/1991
Invited
lecture, “Catecholaminergic systems, stress, and cardiovascular disease. FAES,
NIH, Bethesda, MD, 10/1991
Invited
lecture, “Stress and the Heart,” Division of Heart and Vascular Diseases,
National Heart, Lung, and Blood Institute, 11/1991
Neurology
Grand Rounds: “Heartstrings: Neurocardiology as a New Discipline in Medicine,”
NINDS, NIH, 1/1992.
Chairperson
and invited lecturer, symposium, “Sympathetic Activity and Essential
Hypertension,” 7th International Catecholamine Symposium, Amersterdam, The
Netherlands, 6/1992.
Invited
presentation, “F-18 dopamine as a neuronal marker in the heart,” Institute for
Clinical PET, Fourth International PET Conference & Research Symposium,”
Washington, DC, 10/1992.
Invited
presentation, “New clinical techniques to assess regional sympathoneural
activity,” Third International Symposium on Autonomic Disorders, Nashville, TN,
10/1992.
Invited
presentation, “Clinical applications of catecholamine levels,” Research
Conference, Department of Anesthesiology and Critical Care Medicine, The Johns
Hopkins Hospital, Baltimore, MD, 12/1992.
Invited
lecture, “Stress as a scientific idea,” National Institute of Alcohol Abuse and
Alcoholism, 2/1993.
Invited
speaker, “Cardiac neuroimaging with PET,” Cardiology Department, Uniformed
Services University of the Health Sciences, Bethesda, MD, 2/1993.
Neurology
Grand Rounds, National Naval Medical Center, Bethesda, MD, 3/1993.
Invited
lecture, “Stress and science,” Biological Psychiatry Branch, NIMH, 4/1993.
Invited
speaker, “Biochemical assessment of sympathetic nervous system activity,” NHLBI
Workshop, Clinical Neurobiology of Blood Pressure Regulation, Bethesda, MD,
6/1993.
Invited
speaker, “Sympathetic nervous system and hypertension,” Israeli Society of
Internal Medicine, Jerusalem, Israel, 6/1993.
Invited
lecture, “Is there a third peripheral catecholaminergic system,” Department of
Pharmacology, The Rappaport Faculty of Medical Sciences, Haifa, Israel, 7/1993.
Invited
seminar leader, “Stress as a scientific idea,” Department of Psychiatry, Chaim
Sheba Medical Center, Tel Ha-Shomer, Israel, 7/1993.
Invited
lecture, “Clinical PET scanning of cardiac sympathetic innervation and
function,” Department of Neurology, Division of Cerebrovascular Neurology, The
Johns Hopkins Hospital, 12/1993.
Invited
participant, “Mind-Body-Health Interactions,” MacArthur Foundation Research
Network on Mind-Body Interactions, Clearwater, FL, 2/1994.
Invited
lecture, “Stress, catecholamines, and psychosomatic medicine,” Division of
Behavioral Biology, Department of Psychiatry and Behavioral Sciences, The Johns
Hopkins Medical Institutions, Baltimore, MD, 2/1994.
Invited
lecture, “Stress, catecholamines, and cardiovascular disease: theoretical and
practical issues,” Institut de recherches cliniques de Montreal, Montreal,
Canada, 5/1994.
Invited
lecture, “A homeostatic theory of stress and distress,” The CIANS/ISBM
Conference on Stress and Behavioural Medicine, Prague, Czech Republic, 7/1994.
Invited
lectures, “Anatomical and functional visualization of cardiac sympathetic
innervation in humans,” and “Stress as a scientific idea,” Leiden Working Group
on Cardiovascular Research, Leiden, The Netherlands, 7/1994.
Invited
lecture, “PET scanning of cardiac sympathetic innervation and function,”
University of Nijmegen, Nijmegen, The Netherlands, 7/1994.
Invited lecture,
“PET scanning of cardiac sympathetic innervation and function,” Hadassah
Hospital, Ein Karem, Israel, 7/1994.
Invited
lecture, “PET scanning of cardiac sympathetic innervation and function,”
Beilinson Hospital, Petach Tikve, Israel, 7/1994.
Invited lecture,
“Catecholamines and sympathetic activity in clinical and experimental
hypertension,” Chaim Sheba Medical Center, Tel Ha-Shomer, Israel, 7/1994.
Invited
lecture, “Using PET to access cardiac sympathetic innervation and function,”
NIH Research Festival ‘94 Symposia, 9/1994.
Invited
lecture, “Fluorodopamine PET scanning: The good, the bad, and the ugly,” PET
Department, NIH Clinical Center, 9/1994.
Invited
lecture, “Clinical assessment of sympathetic responses to stress,” First World
Congress on Stress, Bethesda, MD, 10/1994.
Invited
lecture, “Neuronal and non-neuronal sources of dopamine in the periphery,” 5th
International Conference on Peripheral Dopamine, Kyoto, Japan, 10/1994.
Invited
lecture, “PET scanning and clinical evaluation in neurocardiovascular
disorders,” Cardiology Department, National Naval Medical Center, 12/1994.
Introductory
lecture, “Nonspecificity versus primitive specificity of stress responses”
Sixth Symposium on Catecholamines and Other Neurotransmitters in Stress,
Smolenice Castle, Czechoslovakia, 6/1995.
Invited
lecture, “Stress, catecholamines, and cardiovascular disease,” Sixth Symposium
on Catecholamines and Other Neurotransmitters in Stress, Smolenice Castle,
Czechoslovakia, 6/1995.
Clinical
Center Grand Rounds, “PET and neurochemical findings in patients with
dysautonomia,” National Institutes of Health, Bethesda, MD, 1/1996.
Invited
lecture, “Metabolic fate of the sympathoneural imaging agent 6-[18F]fluorodopamine
in humans,” Sixth International Conference on Peripheral Dopamine, Camerino,
Italy, 6/1996.
Invited
lecture, “The sympathetic nervous and adrenomedullary hormonal systems:
Differential responses to stressors,” The Neuroscience and Endocrinology of
Fibromyalgia, National Institues of Health, Bethesda, MD, 7/1996.
Clinical
Center Grand Rounds, “Heartstrings: Visualizing sympathetic innervation and
function in patients with neurocardiologic disorders,” National Institutes of
Health, Bethesda, MD, 6/1997.
NINDS Clinical
Grand Rounds, “Clinical diagnosis of sympathetic neurocirculatory failure,”
National Institutes of Health, Bethesda, MD, 9/1997.
Clinical
Center Grand Rounds, “Molecular and Integrative Medicine: Toward
Rapprochement,” National Institutes of Health, Bethesda, MD, 1/1998.
Lecture, “The
third catecholamine system: Sources of dopamine in the human kidney,”
Laboratory of Kidney and Electrolyte Metabolism, NHLBI, National Institutes of
Health, Bethesda, Maryland, 3/1998.
Lecture,
“Neurogenic autonomic nervous system dysfunction,” Neuroscience Nurse Internship
Program, NINDS, National Institutes of Health, Bethesda, Maryland, 3/1998.
NINDS Clinical
Grand Rounds, “The tendency to faint: Cardiac sympathoinhibition in patients
with neurocardiogenic syncope,” National Institutes of Health, Bethesda, MD,
8/1998.
Invited oral
presentation, “Sources and physiological significance of plasma dopamine
sulfate.” Seventh International Conference on Peripheral Dopamine, Dublin,
Ireland, 8/1998.
Invited
lecture, “Primitive specificity of
stress responses: Clinical demonstrations.” Second World
Congress on Stress, Melbourne, Australia, 10/1998.
Invited
lecture, “Structural and chemical organization of the autonomic neuroeffector
system,” WHO Informal Meeting on the Autonomic Nervous System, Bethesda, MD,
12/1998.
NINDS Clinical
Grand Rounds, “A new sign of sympathetic neurocirculatory failure,” National
Institutes of Health, Bethesda, MD, 3/1999.
Clinical
Center Grand Rounds, “Clinical sympathetic neuroimaging,” National Institutes
of Health, Bethesda, MD, 4/1999.
Symposium Oral Presentation, “Cardiac sympathetic innervation and function in patients with sympathetic neurocirculatory failure and Parkinsonism,” American Academy of Neurology, Toronto, Canada, 4/1999.
Invited
lecture, FAES course, Neuroimmunology, “Catecholamines and stress,” National
Institutes of Health, Bethesda, MD, 3/1999.
Anesthesiology
Grand Rounds, the Johns Hopkins Hospital, “Clinical sympathetic neuroimaging,”
Baltimore, MD, 4/1999.
Symposium Oral Presentation, “Cardiac sympathetic denervation in Parkinson's disease,” Association for Patient Oriented Research, Atlantic City, NJ, 4/1999.
NINDS Clinical
Grand Rounds, “Cardiac sympathoinhibition in Parkinson’s disease,” National
Institutes of Health, Bethesda, MD, 5/1999.
Invited
lecture, “Autonomic failure syndromes.” Neuroscience Nursing Internship
Program, NINDS, National Institutes of Health, Bethesda, MD, 6/1999.
Invited
lecture, “Stressor specific activation of catecholaminergic systems: Clinical
demonstrations.” Seventh Symposium on Catecholamines and Other
Neurotransmitters in Stress, Smolenice Castle, Slovakia, 7/1999.
NINDS Clinical
Grand Rounds, “Sympathetic innervation and function in reflex sympathetic
dystrophy,” National Institutes of Health, Bethesda, MD, 8/1999.
Clinical Staff
Conference, NIH Clinical Center, “Recent advances in genetics, diagnosis,
localization, and treatment of pheochromocytoma,” National Institutes of
Health, Bethesda, MD, 9/1999.
Symposium Oral Presentation, “Cardiac sympathetic denervation in Parkinson's disease,” American Autonomic Society, Hawaii, 10/1999.
Invited
lecture, FAES course, PET Scanning, “Neurocardiology and the sympathetic
nervous system,” National Institutes of Health, Bethesda, MD, 12/1999.
Invited
lecture, “Clinical Laboratory Evaluation of Autonomic Failure Syndromes,”
Israel Society of Internal Medicine, Kfar Hamacabiah, Israel, 3/2000.
NINDS Clinical
Grand Rounds, “Concepts of integrative medicine: Applications to
neurocardiologic disorders,” National Institutes of Health, Bethesda, MD,
3/2000.
Invited
lecture, “Cardiac sympathetic denervation in Parkinson’s disease,” PET
Department, NIH Clinical Center, 3/2000.
Invited
lecture, “Cardiac sympathetic denervation in Parkinson’s disease,” Second
Annual Meeting, Association for Patient-Oriented Research, Arlington, VA,
3/2000.
Seminar,
“Catecholamines and stress,” Foundation for Advanced Education in the Sciences
course, Neuroimmunology, Bethesda, Maryland, 4/2000.
Lecture,
“Autonomic nervous system disorders,” Neuroscience Nurse Internship Program,
NINDS, National Institutes of Health, Bethesda, Maryland, 4/2000.
Invited
lecture, “PET and neurochemical approaches to examine sympathetic innervation
and function in the human heart: Clinical applications in neurocardiological
disorders,” Cardiovascular Science Meeting, Uppsala, Sweden, 5/2000.
Moderator,
Clinical Staff Conference, NIH Clinical Center, “Tugged Heartstrings:
Dysautonomias,” National Institutes of Health, Bethesda, MD, 5/2000.
Invited
lecture, “Stressor specificity of neuroendocrine responses: Clinical
demonstrations.” Third World Congress on Stress, Dublin, Ireland, 9/2000.
Seminar,
“Kinetic model for the fate of 6-[18F]fluorodopamine
in the human heart: A novel means to assess cardiac sympathetic function,” NIH
PET Department, 10/2000.
How-to Session,
“Evaluation of orthostatic hypotension,” American Heart Association, New
Orleans, LA, 11/2000.
Lecture,
“Neurocardiology,” FAES Course on Positron Emission Tomography: Principles and
Applications, NIH, 11/2000.
Lecture,
“Recent advances in the diagnosis of pheochromocytoma,” Department of Medicine,
Chaim Sheba Medical Center, Tel Ha-Shomer, Israel, 1/2001
Lecture, “What
do plasma catechols mean?” New York Medical College, Valhalla, NY, 1/2001
Lecture, “PET
scanning of cardiac sympathetic innervation and function in neurocardiologic
disorders” New York Medical College, Valhalla, NY, 1/2001
NINDS Clinical
Grand Rounds, “What do plasma catechols mean?” National Institutes of Health,
Bethesda, MD, 1/2001
Invited
lecture, “Neurocardiology,” Department of Neurology, VA Medical Center,
Washington, DC, 2/2001
Seminar,
“Catecholamines and stress,” Foundation for Advanced Education in the Sciences
course, Neuroimmunology, Bethesda, Maryland, 2/2001.
NINDS Clinical
Grand Rounds, “Why people faint: Sympathoadrenal imbalance as the proximate
cause of neurocardiogenic syncope.” National Institutes of Health, Bethesda,
MD, 4/2001
Faculty,
Evaluation and Management of Autonomic Disorders, 2001 Annual Meeting, American
Academy of Neurology, Philadelphia, PA, 5/2001.
Invited
seminars, “Stress and the sympathoadrenal system: New ideas about old ideas.”
Clinical Neuroendocrinology Branch, NIMH, 6-7/2001.
Chair,
“Regulation of blood pressure in health and disease.” Central Mechanisms of
Cardiovascular Control—Integrative, Cellular and Molecular Aspects (Satellite
of IUPS 2001), Sydney, Australia, 8/2001.
Seminar,
“People who faint: Cardiac sympathetic innervation in neurocardiogenic
syncope.” NIH PET Department, Bethesda, MD, 10/2001.
Invited
lecture, “Stress, the autonomic nervous system, and the inner world.” NINDS
lecture series, “Unraveling Mysteries of the Brain.” Bethesda, MD, 11/2001.
NINDS Clinical
Grand Rounds, “Dysautonomia in Parkinson’s disease.” National Institutes of
Health, Bethesda, MD, 12/2001.
Invited lecture,
“Dysautonomia in Parkinson’s disease.” Chaim Sheba Medical Center,
Tel-Ha-Shomer, and Rabin Medical Center, Petach Tikve, Israel, 12/2001.
Seminar,
“Stress, the automatic nervous system, and the inner world,” FAES course,
Neuroimmunology, Bethesda, Maryland, 2/2002.
Invited
Expert, “Biological Mechanisms of Psychosocial Effects of Disease,” Division of
Cancer Control and Population Sciences, NCI, Bethesda, MD, 2/2002.
Clinical
Endocrinology Grand Rounds, “Stress as a Scientific Idea,” NICHD, NIH, Bethesda,
MD, 4/2002.
Clinical
Center Grand Rounds, “Dysautonomia in Parkinson’s Disease,” NIH, Bethesda, MD,
5/2002.
Invited
lecture, “Sources of NE and its metabolites in accessible tissues in humans.”
XXIII Congress of the Collegium Internationale Neuro-Psychopharmacologicum.
Montreal, Canada, 6/2002.
Neurology
Grand Rounds, “Dysautonomia in Parkinson’s Disease,” VA Medical Center,
Washington, DC, 7/2002.
Invited
Lectures, “The autonomic nervous system and dysautonomias” and
“Neurotransmitters,” Second Patient Conference, National Dysautonomia Research
Foundation, Washington, DC, 7/2002
Seminar, “A
syndrome of neurogenic orthostatic hypotension, cardiac sympathetic
denervation, and subtle parkinsonism.” PET Interest Group, NIH, Bethesda, MD,
9/2002.
Invited Lecture,
“Dysautonomia in familial Parkinson’s disease,” NIH Workshop, Inherited
Dysuautonomias, Bethesda, MD, 10/2002.
Invited
Lectures, “The autonomic nervous system and cardiovascular regulation,” and
“Disorders of autonomic regulation of the cardiovascular system,” Saul Farber
Distinguished Lectureship, Tel Aviv University Sackler School of Medicine,
Israel, 10/2002.
Medical Grand
Rounds, “Why people faint,” Rambam Hospital, Haifa, 10/2002.